Laboratory calculator
Semaglutide Reconstitution Calculator (10 mg vial)
Worked example
Worked example: a 10 mg vial of Semaglutide reconstituted with 2 mL of bacteriostatic water has a concentration of 5 mg/mL. A 250 mcg example amount is a 0.05 mL aliquot, which reads 5 units on a U-100 syringe, and the vial holds 40 aliquots of that size.
Reconstitution calculator
Sizes in the Pepcore catalogue5 mg
- Concentration
- 5 mg/mL
- Volume to draw
- 0.05 mL
- Units on a U-100 syringe
- 5 units
- Draws per vial
- 40
How it works
- Concentration = vial mass / water volume: 10 mg / 2 mL = 5 mg/mL.
- Aliquot volume = target amount / concentration: 0.25 mg / 5 mg/mL = 0.05 mL.
- Units on a U-100 syringe = mL x 100 = 5.
- Aliquots per vial = vial mass in mcg / target amount = 10,000 / 250.
Frequently asked questions
How much water does a 10 mg vial of Semaglutide need for 5 mg/mL?
Concentration is vial mass divided by water volume: 10 mg / 2 mL = 5 mg/mL. Change the water volume in the calculator to see how the concentration and the syringe reading move together.
How many units on a U-100 syringe is a 250 mcg example amount of Semaglutide?
At 5 mg/mL a 250 mcg example amount is 0.05 mL, which is 5 units because 1 unit on a U-100 syringe equals 0.01 mL.
How many 250 mcg aliquots are in a 10 mg vial of Semaglutide?
10 mg is 10,000 mcg, and 10,000 mcg divided by 250 mcg gives 40 aliquots, before allowing for volume lost to priming and syringe dead space.